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Revista Médica del Uruguay
Print version ISSN 0303-3295On-line version ISSN 1688-0390
Abstract
SCARLATTO, Bruno; KOHN, Sofía and MANZANARES, William. Thrombotic microangiopathy as a complication of acute pancreatitis. Rev. Méd. Urug. [online]. 2022, vol.38, n.4, e703. Epub Dec 01, 2022. ISSN 0303-3295. https://doi.org/10.29193/rmu.38.4.11.
Thrombotic thrombocytopenic purpura is rather an unusual thrombotic microangiopathy characterized by hemolytic anemia and plateletopenia which results in high morbimortality rates. The most frequent form of this disease is immune thrombotic thrombocytopenic purpura, also known as acquired thrombotic thrombocytopenic purpura, which is caused by enzime deficiency disintegrin-like and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13) that is secondary to antibodies in plasma. The study presents the case of a patient with a diagnosis of acute pancreatitis with a rare complication of thrombotic thrombocytopenic purpura which is exceptional in the clinical practice.
Keywords : Acute pancreatitis; Thrombotic thrombocytopenic purpura.