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Revista Médica del Uruguay
versión impresa ISSN 0303-3295versión On-line ISSN 1688-0390
Resumen
PRITSCH, Cecilia; FINOZZI, Rosa y NEIRA, Natalia. The role of thyroglobulin detection in washout fluid from fine-needle aspiration biopsies to diagnose gland metastases in thyroid cancer follow up. Rev. Méd. Urug. [online]. 2022, vol.38, n.3, e201. Epub 01-Sep-2022. ISSN 0303-3295. https://doi.org/10.29193/rmu.38.3.1.
Recurrence of differentiated thyroid cancer (DTC) in the cervix is 5-20% of cases. Fine-needle aspiration cytology of adenopathies has been used to confirm ultrasound findings when suspicions of being malignant.
The study aims to evaluate usefulness of fine-needle aspiration of lymph gland to diagnose gland metastases in patients over 18 years old under papillary thyroid cancer follow-up. Retrospective, descriptive and observational study in a 14-patient-sample, mainly female (71,4%), with an average age of 40.9 ± 2.9 years old.
Results:
single tumor focus papillary thyroid cancer was the most common type of thyroid cancer found. 50% of the 22 suspicious glands had FNATg ≥1ng/ml. All reactive adenitis had measurements < 1ng/ml, whereas metastatic adenopathies results were ≥ 1ng/ml. 85.7% of patients had anti-TG Ac ≥ 1ng/ml (5 patients with FNATg values ≥1ng/ml and 7 patients with FNATg < 1ng/ml), 14.3% of which obtained results < 10 UI/ml (all of them with FN1 ng/ml). Gland emptying was performed in 4 cases, and papillary thyroid cancer metastases was found in all of them.
Conclusions:
FNATg is a good study to diagnose gland metastases in patients under differentiated thyroid cancer follow-up. Given the results of this study, supported by a bibliographic search, the use of FNATg has a great diagnostic value to detect gland metastases in the follow up of differentiated thyroid cancer, and thus it is recommended along with cytological and/or pathology studies.
Palabras clave : Thyroglobulin; Thyroid cancer; Punctures; Adenopathies..
