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Revista Médica del Uruguay

Print version ISSN 0303-3295On-line version ISSN 1688-0390


SPERANZA MOURINE, Noelia et al. Description of benzodiazepines availability and regulation in several countries of Latin America, 2022. Rev. Méd. Urug. [online]. 2022, vol.38, n.2, e201.  Epub June 01, 2022. ISSN 0303-3295.


benzodiazepines constitute a widely prescribed group of drugs around the world, since they appeared in the sixties. This study aims to identify the availability, prescription modalities and dispensing of benzodiazepines in different countries around Latin America, as per the legal provisions in force in each of the countries participating in the study.


observational, descriptive, transversal study based on the information available in 2022 about all the member countries of the Network Medicines Information Centers of Latin America and the Caribbean (CIMLAC Network) that were part of the study. The databases of regulatory authorities were used and the legal provisions in force and relevant documents were consulted in order to obtain information on benzodiazepines dispensing and prescription in each country.


twelve out of the 20 CIMLAC Network member countries completed the study. The total number of benzodiazepines available in the study ranged from 6 to 12 (mean was 9), and 5 of them on average were included in the national essential medications lists. Most countries have benzodiazepines fixed dose combinations and in all countries a special medical prescription is needed. More than half of the countries have national recommendations.


the wide availability of benzodiazepines in the market, the existence of fixed-dose combinations and the lack of national recommendations may constitute factors that contribute to the irrational use of this group of drugs.

Keywords : Benzodiazepines; Medication use; Drug information services; Latin America.

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