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Revista Médica del Uruguay
Print version ISSN 0303-3295On-line version ISSN 1688-0390
Abstract
MAINARDI, Victoria et al. Results of the National Program of Liver Transplantation in Uruguay 10 years after it was initiated. Rev. Méd. Urug. [online]. 2020, vol.36, n.4, pp.4-36. Epub Dec 01, 2020. ISSN 0303-3295. https://doi.org/10.29193/rmu.36.4.2.
Introduction:
liver transplantation constitutes the first therapy chosen by patients with severe and irreversible liver conditions, when no effective alternative options are available.
Measurement of quality indicators allow for the detection of problems that may be solved in order to optimize results.
Objective:
to present the results obtained in the National Program of Liver Transplantation in Uruguay, 10 years after its implementation and to compare them to international quality standards.
Method:
retrospective study of liver transplantations performed from July 14, 2009 through July 14, 2019.
Results:
N: 190 Liver transplantations (LT). Average age: 45 years old. Gender: 60% male. MELD average MELD (Model for End-stage Liver Disease) upon LT: 21. Main indications: cirrhosis he(59%) y hepatocarcinoma (21%). Post-surgery mortality: 7.4% and peri-operative mortality 2.1% (standards <10 and 1%). Re-transplantation rate: early 3.7% and late 4.2% (standards <5% and 8%). Reoperation rate: 13.1% (standard <10%) and of non-primary function: 2.6% (standard <2%). Survival: 86.6% per year, 81.8% after 3 years, 77.4% after 5 and 63.2% after 10 years (standards >80, 75, 70 and 60%). Patients assessed in less than 30 days: 47% (standard >75%). Non-implanted livers with no objective cause rate: 0.5% (standard <1%). 86% of users stated they were satisfied (standard >80%). Mortality in the waiting list: 19% (standard <15%). Early mortality with functioning liver: 1% (standard <1%).
Conclusions:
national Program of Liver Transplantation in Uruguay meets most quality indicators standards, evidencing survival results that are above international standards.
Keywords : Liver transplantation; Survival; Quality improvement; Quality indicators; Uruguay.