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Revista Médica del Uruguay

Print version ISSN 0303-3295On-line version ISSN 1688-0390

Abstract

CASTRO, Álvaro et al. Diagnostic value of CT and Pet CT for detection of peritoneal carcinomatosis. Preliminary study. Rev. Méd. Urug. [online]. 2020, vol.36, n.2, pp.99-121.  Epub June 01, 2020. ISSN 0303-3295.  https://doi.org/10.29193/rmu.36.2.5.

Imagenology contributes to the accurate diagnosis of peritoneal compromise in the assessment of peritoneal carcinomatosis, although its effectiveness is still limited. CT is the most frequently used study and PET/CT is graduallly more requested in the assessment of different neoplasms. This study aims to assess performance of CT and PET/CT for diagnosis of peritoneal carcinomatosis in digestive and gynecological tumours.

Method:

retrospective, observational study of 11 cases operated on peritoneal carcinomatosis after a CT and/or PET/CT had been performed. The results of both image studies were analysed separately and altogether and they were subsequently compared to intraoperative and pathology studies.

Results:

CT matched findings in 8 out of 10 cases (sensitivity 78%, specificity 100%, positive predictive value 100%, negative predictive value 33%), whereas PET/TC matched in 9 out of 11 patients (sensitivity 100%, PPV 81%). When considered together, sensitivity was 100% y el PPV de 82%.

Conclusions:

the results of the study confirm imagenology studies overestimate peritoneal carcinomatosis based on the characteristics of nodules and its uptake pattern. In CT/PET, SUV> 6 could increase the probability of diagnosing carcinomatosis. This small series of cases enables our suggesting CT and 18F-FDG PET-TC to be requested and analysed together to increase its efficiency, although surgical exploration continues to be the most effective method to diagnose and assess peritoneal carcinomatosis.

Keywords : Peritoneal neoplasms; Carcinoma; Peritoneum; Hyperthermia, induced; Positron-emission tomography; Tomography, X-ray computed.

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