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Revista Médica del Uruguay

On-line version ISSN 1688-0390

Abstract

MENDEZ, Gonzalo; ANDRADE, Rodrigo; LOPEZ, Maynés  and  LLAMBI, Laura. Pneumocistis jiroveccii como causa de fiebre de origen desconocido en paciente con dermatomiositis y tromboembolismo pulmonar. Rev. Méd. Urug. [online]. 2015, vol.31, n.3, pp.214-220. ISSN 1688-0390.

Abstract Dermatomyositis (DM), the same as other auto-immune diseases, has been reported in several studies as a risk factor for a venous thromboembolic disease. Also, given immunity alterations caused by the disease itself, along with the immunodepression that characterizes treatment, these patients are likely to present infectious complications, many of them due to opportunistic germs such as Pneumocystis jirovecci (PJ). Diagnostic criteria for fever of unknown origin (FUO) have been long discussed. Lately, new categories that are different to the classic FUO have been proposed, as is the one affecting immunodepressed patients, where both the etiology and presentation vary. Over 200 causes for FUO have been described, PJ being among them. The clinical case of a female patient diagnosed with DM is described in the study, who, in spite of thromboprofilaxis presented a pulmonary thromboembolism episode. Likewise, during hospitalization, the patient evidenced FUO. After an extensive search, PJ was isolated and treatment was applied, resulting in an excellent clinical response.

Keywords : PNEUMOCYSTIS JIROVECII; FEVER OF UNKNOWN ORIGIN; DERMATOMYOSITIS; PULMONARY EMBOLISM.

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