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Revista Médica del Uruguay

versión On-line ISSN 1688-0390


LEMA SPINELLI, Sebastián; TOLEDO SUAREZ, Sebastián; CARRACEDO, María Rosa  y  RODRIGUEZ ALMADA, Hugo. La ética de la investigación en seres humanos en debate. Rev. Méd. Urug. [online]. 2013, vol.29, n.4, pp.242-247. ISSN 1688-0390.

Abstract Research involving human beings enables improvement of diagnosis and treatment of diseases. Without prejudice of its doubtless benefits for humanity, we need to bear in mind that historically, this kind of research proved that every time it moved away from moral reflection and social control, aberrant facts took place and several human rights were ran over (before, during and after World War II). Today, we witness the ongoing debate between trends that favor an increased ethical flexibility that allows better times and costs of research, and the opposite trends that believe a double ethical standard resulting in vulnerable people and populations being mere means for the accomplishment of benefits for humanity or science is unacceptable. The debate focuses on whether or not to open the door to the use of placebo in controlled clinical trials when there is a well known treatment, and whether or not to ensure participants are guaranteed the benefits of treatment for free. Until now, the relevant legal provisions in force (Decree 379/008) have endured the trend to increase flexibility. However, our country cannot ignore the global debate on this issue. Ethical regulations need to be revised through an ongoing ethical reflection. Notwithstanding this process, this update must not give up agreed ethical standards that prioritize the protection of participants in research over any other interest.


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