Abstract

GRUSS, Ana Inés et al. Primer caso en Uruguay de tuberculosis asociada a terapia con agentes biológicos: reporte de un caso clínico. Rev. Méd. Urug. [online]. 2012, vol.28, n.3, pp.205-208. ISSN 1688-0390.

Abstract Biologic therapies with anti-tumor necrosis factor alpha (TNF-?) monoclonal antibodies were a revolution in the treatment of rheumatoid arthritis. The use of antibodies implies a high risk of developing pulmonary tuberculosis and thus a thorough assessment is necessary, both upon the initiation of treatment and during patient follow up, to rule out a latent infection or active tuberculosis. The study presents the first clinical case of pulmonary tuberculosis associated with biologic therapy described in Uruguay (adalimumab).

Keywords : ARTHRITIS, RHEUMATOID [complications]; BIOLOGICAL THERAPY [adverse effects]; TUBERCULOSIS.

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