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Revista Médica del Uruguay

On-line version ISSN 1688-0390


VARELA, Gustavo et al. Escherichia coli enteropatógeno clásico (EPEC) asociado a casos de diarrea en niños usuarios del Hospital Pereira Rossell. Aspectos clínicos y características de las cepas involucradas. Rev. Méd. Urug. [online]. 2007, vol.23, n.3, pp.153-163. ISSN 1688-0390.

Summary Background: acute diarrhea disease (EDA) is responsible of 12.000 deaths per day in Asia, Africa and Latin America. Classic Enteropathogenic Escherichia coli (EPEC) is an important virotype associated with EDA episodes in children under five years of those regions. Objectives: to know clinical manifestations of diarrhea cases due to EPEC in children users of a Public Health centre and to establish the characteristics of involved strains. Methods: ninety-five children with EDA were studied. Every child underwent clinical history and copromi-crobiologic studies. EPEC strains were detected by reaction chain polymerase (PCR) of eae and were completely characterized including determination of genetic variations of eae and bfp gens. Results: twenty-six EPEC strains were isolated, 15 typical and 11 atypical. The most frequent variant of bfp was b and 9 variants of eae were seen. Most of the infected children with EPEC presented watery diarrhea associated with vomiting, and fever in half of the cases. Blood and fecal leukocytes were found in 20% of the children. Conclusions: as it happens in other areas, typical EPEC strains appear as frequent enteropathogens in this group of children. Atypical cultures also play an important rol as agents of diarrhea. Clinical characteristics do not differ from those of children with diarrhea in developed countries; no differences were seen with other agents.

Keywords : DIARREA INFANTIL [etiología]; DIARREA INFANTIL [epidemiología]; DIARREA INFANTIL [microbiología]; ENFERMEDAD AGUDA.; HECES [microbiología]; INFECCIONES POR ESCHERICHIA COLI [microbiología]; ESCHERICHIA COLI [aislamiento y purificación.]; ESCHERICHIA COLI [patogenicidad].

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