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Revista Médica del Uruguay

On-line version ISSN 1688-0390


LEBORGNE, Felix; MEZZERA, Julieta; LEBORGNE DEUS, José  and  AGUIAR, Sergio. Irradiación posprostatectomía del cáncer de próstata: Un análisis preliminar. Rev. Méd. Urug. [online]. 2005, vol.21, n.3, pp.194-199. ISSN 1688-0390.

Summary The results of radiotherapy after radical prostatectomy for adenocarcinoma of the prostate were reviewed. Sixty two consecutive patients treated from 1994 through 2002 were analysed. Twenty patients received adjuvant radiotherapy due to high risk factors for local recurrence following surgery, and 42 patients received postoperative irradiation for biochemical failure after prostatectomy (17 of these patients had also a palpable recurrence in the pelvis). The five-year actuarial free survival from biochemical failure, cause specific survival and overall survival were 90%, 100% and 100% for patients treated with adjuvant radiotherapy, and 45%, 97% and 95% for those treated with salvage radiotherapy, respectively. In this latter group, when no hormone therapy was added to irradiation, the finding of a decline in their PSA levels at 50 Gy showed a trend towards an improved biochemical control. Late urinary complications after radiotherapy were more frequent than those observed after radical radiotherapy alone as primary treatment.


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