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Revista Médica del Uruguay

On-line version ISSN 1688-0390


RODRIGUEZ, Susana; NEGRIN, Alba  and  BURGER, Mabel. Efecto adverso por suero antibothrópico. Rev. Méd. Urug. [online]. 2004, vol.20, n.3, pp.228-232. ISSN 1688-0390.

Summary Ophidian accidents in Uruguay have a variable annual prevalence, from 80 to 100 cases. Most of the reported cases are due to Bothrops gender species (60 to 70 cases a year), and need to be treated with antibothropic serum. Since 1986 the Comisión Nacional de Ofidismo del Ministerio de Salud Pública has been producing a national protocol on diagnosis, treatment and follow-up. A year earlier, a synthesis of a national anti-ophidian serum commenced. Since 1999, adverse reactions were seen when national anti-ophidian serum was used. These events were coincident with some difficulties detected on quality controls of the serum and a wider sensitivity about detecting adverse reactions. A case report where a severe and unfrequent adverse reaction to antibothropic serum is presented. Etiopathogenesis of the reaction and its correlations to serum are discussed.

Keywords : ANTIVENENOS [efectos].

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