Archivos de Pediatría del Uruguay
versão impressa ISSN 0004-0584
MENDEZ, VIRGINIA et al. Colestasis neonatal: evolución de los pacientes diagnosticados entre 1983 y 2000 en dos servicios gastroenterológicos de referencia de Montevideo. Arch. Pediatr. Urug. [online]. 2005, vol.76, n.3, pp. 210-221. ISSN 0004-0584.
Summary This is a descriptive study conducted to determine the course of patients with a history of neonatal cholestasis (NC) with regard various conditions, and to compare it with children’s course at other centres. The children enrolled had been diagnosed NC at the Gastroenterology Department of DEMEQUI and CHPR in the 1983-2000 period. Data were drawn from pre-coded cards completed when patients were seen for the first time and from their clinical records. The children were summoned for an appointment where their clinical case, physical examination and lab testing were recorded in coded cards. Data were analyzed with Epi Info 6. NC was diagnosed in 51 children from 1983 to 2000; 37 in DEMEQUI and 14 in CHPR. The etiologies, clinical and laboratory testing are discussed and described. Patients’ course was similar to that described in other series, except for transplanted children, who had a worse course, and the cases of neonatal hepatitis, all of which had a good course, probably because several had transient neonatal hepatitis. Referral to tertiary care was typically late and should be especially addressed at continuing medical education activities. There is a need to promote a better follow-up and nutritional support for patients and to obtain the resources required to organize a team of paediatric experts to monitor these children in the country before and after transplantation, centralizing work and coordinating with the transplantation centre team abroad, until this technique is covered in Uruguay
Palavras-chave : CHOLESTASIS; BILIARY ATRESIA; INFANT, NEWBORN.